Platelet Factor 4

A CXC chemokine that is found in the alpha granules of PLATELETS. The protein has a molecular size of 7800 kDa and can occur as a monomer, a dimer or a tetramer depending upon its concentration in solution. Platelet factor 4 has a high affinity for HEPARIN and is often found complexed with GLYCOPROTEINS such as PROTEIN C.

Also Known As:

Heparin Neutralizing Protein; PF4 (Platelet Factor 4); gamma-Thromboglobulin; CXCL4, Chemokine; Chemokine, CXCL4; gamma Thromboglobulin; Antiheparin Factor; CXCL4 Chemokine; Chemokine CXCL4; Blood platelet factor 4

Pharmalogical Action Categories:

Coagulants

Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Chemokines: 25302
        CXC Chemokines: 2059
        Platelet Factor 4: 1078
  - Blood Proteins: 12679
    - Blood Coagulation Factors: 5500
      - Platelet Factor 4: 1078
- Peptides: 84029
  - Intercellular Signaling Peptides and Proteins: 30151
    - Cytokines: 168239
      - Chemokines: 25302
        CXC Chemokines: 2059
        Platelet Factor 4: 1078
Biological Factors: 2560
- Intercellular Signaling Peptides and Proteins: 30151
  - Cytokines: 168239
    - Chemokines: 25302
      - CXC Chemokines: 2059
        Platelet Factor 4: 1078
- Blood Coagulation Factors: 5500
  - Platelet Factor 4: 1078
- Chemotactic Factors: 3794
  - Chemokines: 25302
    - CXC Chemokines: 2059
      - Platelet Factor 4: 1078
- Inflammation Mediators: 1126
  - Chemokines: 25302
    - CXC Chemokines: 2059
      - Platelet Factor 4: 1078

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